Jurnal Farmasi dan Ilmu Kefarmasian Indonesia (JFIKI) Vol 6 No 2

Umi, Athiyah (2019) Jurnal Farmasi dan Ilmu Kefarmasian Indonesia (JFIKI) Vol 6 No 2. Jurnal Farmasi dan Ilmu Kefarmasian Indonesia (JFIKI), 6 (2). pp. 51-90. ISSN 2406-9388

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Abstract

Background: Recently, the topical antiacne medicines have been circulating in the form of gels and creams, but there are still a few of them contain herbs, as an active ingredient or agent which potentially prevent and treat acne such as pegagan (Centella asiatica (L.) Urb) because of antibacterial activity. Objective: To develop a stable formulation of pegagan gel. Methods: Testing of pegagan formulation according to the evaluation requirements based on gel concentration of 7%, 8%, and 9% as well organoleptic testing, pH, and viscosity. Extract of pegagan was added to the formula at concentration of 2.5% and 5%. Evaluation of the formula includes homogeneity, acidity test, viscosity and spread potency. Results: Average pH of the formula was 6.66. There was a slight difference of viscosity between First Formula and Second Formula. Both of First Formula and Second Formula showed homogeneity and dispersion capacity in accordance with the requirements. Conclusion: During 14 days of testing, Second Formula with 5% extract concentration more stable than Second Formula with an extract concentration of 2.5%.

Item Type:	Article
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Library of Congress Subject Areas > P Language and Literature > Farmasi Library of Congress Subject Areas > P Language and Literature > Fakultas Farmasi > Farmasi Fakultas Farmasi > Farmasi
Depositing User:	Unnamed user with email repo@umsb.ac.id
Date Deposited:	05 Sep 2022 08:17
Last Modified:	06 Sep 2022 02:49
URI:	http://eprints.umsb.ac.id/id/eprint/353

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