Advances in tumor-endothelial cells co-culture and interaction on microfluidics

Weiwei Li,, Weiwei Li, and Mashooq Khan,, Mashooq Khan, and Sifeng Mao,, Sifeng Mao, (2017) Advances in tumor-endothelial cells co-culture and interaction on microfluidics. Tsinghua University, Beijing 100084, China. pp. 1-68.

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Abstract

The metastasis in which the cancer cells degrade the extracellular matrix (ECM) and invade to the sur- rounding and far tissues of the body is the leading cause of mortality in cancer patients. With a lot of advancement in the field, yet the biological cause of metastasis are poorly understood. The microfluidic system provides advanced technology to reconstruct a variety of in vivo-like environment for studying the interactions between tumor cells (TCs) and endothelial cells (ECs). This review gives a brief account of both two-dimensional models and three-dimensional microfluidic systems for the analysis of TCs-ECs co- culture as well as their applications to anti-cancer drug screening. Furthermore, the advanced methods for analyzing cell-to-cell interactions at single-cell level were also discussed. & 2018 Xi'an Jiaotong University. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

Item Type: Article
Divisions: Library of Congress Subject Areas > P Language and Literature > Farmasi
Library of Congress Subject Areas > P Language and Literature > Fakultas Farmasi > Farmasi
Fakultas Farmasi > Farmasi
Depositing User: Unnamed user with email repo@umsb.ac.id
Date Deposited: 28 Sep 2022 02:26
Last Modified: 28 Sep 2022 02:26
URI: http://eprints.umsb.ac.id/id/eprint/468

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